Histone Deacetylases and Radiation Therapy: Current Status and Gazing Towards the Future
نویسنده
چکیده
*Correspondence: Athanassios Vassilopoulos, Department of Radiation Oncology, Laboratory for Molecular Cancer Biology, Robert H Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA, Tel: 312503-0727; E-mail: athanasios.vasilopoulos@ northwestern.edu Received Date: 19 May 2017 Accepted Date: 01 Jun 2017 Published Date: 10 Jun 2017 Citation: Chang ED, Vassilopoulos A. Histone Deacetylases and Radiation Therapy: Current Status and Gazing Towards the Future. Ann Radiat Ther Oncol. 2017; 1(1): 1002.
منابع مشابه
Effects of Trichostatin A on the Histone Deacetylases (HDACs), Intrinsic Apoptotic Pathway, p21/Waf1/Cip1, and p53 in Human Neuroblastoma, Glioblastoma, Hepatocellular Carcinoma, and Colon Cancer Cell Lines
Background: The aberrant and altered patterns of gene expression play an important role in the biology of cancer and tumorigenesis. DNA methylation and histone deacetylation are the most studied epigenetic mechanisms. Histone deacetylase inhibitors (HDACIs) such as valproic acid (VPA) and trichostatin A (TSA) are a group of anticancer compounds for the treatment of solid and hematological canc...
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